All researchers:

Marco Salvemini,
Remo Sanges
Vincenza Colonna
Giuseppe Saccone
Serena Aceto

Marco Salvemini

Marco is the Principal Investigator of this project and he is Researcher and Lecturer in Genetics at the Department of Biology of the University of Studies of Naples Federico II.

His main scientific interest is the study of sex determination in Insects to increase knowledge about the molecular mechanisms regulating this important developmental event and to produce new biotechnological tools for the control of agricultural pests and disease vectors.

Marco contributed to the discovery of the key gene for female sexual development in Insects, the Cctra gene, isolated in Naples in the Mediterranean fruit fly Ceratitis capitata and present in almost all the insect species studied to date, he shown that the Cctra-2 gene has a key role in the maintenance of the activation state of the Cctra in the female sex, and he studied the genes at the bottom of the sex determination cascade in the mosquito Aedes aegypti.

In 2005 and 2006 Marco was at the CIB-CSIC, Madrid, Spain, to isolate and study the tra gene in fruit fly species of the Anastrepha genre. In the last years Marco started to apply Next Generation Sequencing and bioinformatics to his studies to approach the general problem of identifying sex-specifically and sex-biased genes by comparing dipteran sexed de novo assembled transcriptomes from various developmental stages and species. Marco is also developing new graphical interfaces and on-line databases for comparative genomics and digital gene expression analyses in biological samples with opposite sexes.

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